

Suitable for individuals experiencing general fatigue who need liver support and mild physical recovery. Hepalyse Drink II combines Liver Hydrolysate, Taurine, B vitamins, and herbal extracts to help replenish essential nutrients, support liver function, enhance energy metabolism, and improve fatigue and physical weakness.
Country of Origin: Japan
Brand: Hepalyse (ヘパリーゼ)
Manufacturer: Zeria Pharmaceutical Co., Ltd.
Packaging: 50 mL bottle; Box of 10 × 50 mL bottles
Suggested Retail Price (Japan):
Main benefits:
– Helps relieve general physical fatigue and weakness
– Supports liver, stomach, and intestinal function
– Provides nutritional support during physical exhaustion, illness, or recovery
– Supports energy metabolism with Liver Hydrolysate, Taurine, B Vitamins, and herbal extracts
Directions for use:
– Adults aged 15 years and over
– Take 1 bottle (50 mL) once daily
– Do not use for children under 15 years of age
The liver is one of the body’s most important metabolic organs, performing hundreds of essential functions, including nutrient metabolism, protein synthesis, and detoxification. Modern lifestyles, such as irregular eating habits, alcohol consumption, physical overexertion, and prolonged stress, can increase the liver’s metabolic workload and contribute to general fatigue.
Hepalyse Drink II is a 50 mL oral liquid classified as a Class 3 OTC medicine in Japan. It contains Liver Hydrolysate, Taurine, B vitamins, and traditional herbal extracts to provide nutritional support, support normal liver function, and help relieve general physical fatigue.
As an OTC medicine, Hepalyse Drink II is manufactured under Japan’s pharmaceutical regulations and is approved for sale with standardized quality, safety, and labeling requirements.
The key active ingredient in Hepalyse Drink II is Liver Hydrolysate (200 mg), which is produced by enzymatically hydrolyzing animal liver into small peptides and amino acids that are more readily absorbed by the body.
These nutrients provide building blocks that support normal liver function, cellular nutrition, and energy metabolism.
The formula is further complemented by:
Together, these ingredients provide comprehensive nutritional support for individuals experiencing general fatigue, physical weakness, or increased metabolic demands.
Hepalyse Drink II is a Japanese Class 3 OTC medicine formulated to support normal liver function, help relieve general physical fatigue, and provide nutritional support during illness, recovery, or periods of physical exhaustion.
It is suitable for adults aged 15 years and older who experience general fatigue, physical weakness, reduced appetite, or need nutritional support during recovery. It is not intended for children under 15 years of age.
Adults (15 years and older) should take one 50 mL bottle once daily. Follow the directions on the product label and do not exceed the recommended dosage.
No. Hepalyse Plus II is not recommended for individuals under 15 years of age, according to the manufacturer’s instructions.
No. Hepalyse Drink II does not contain caffeine. Its formula is based on Liver Hydrolysate, Taurine, B vitamins, and traditional herbal extracts to support energy metabolism and general physical condition.
Do not use the product if you are allergic to any of its ingredients. If you are pregnant, breastfeeding, taking medication, or receiving medical treatment, consult a healthcare professional before use. If any unusual symptoms occur, discontinue use and seek medical advice.
Zeria Pharmaceutical Co., Ltd. Hepalyse Plus II – Official Product Information. Official information on indications, active ingredients, dosage, OTC classification, packaging, and precautions.
Japan Self-Medication Database Center (JSM-DBC). OTC Medicine Search – Hepalyse Plus II. Japanese OTC database providing product classification, ingredients, packaging, JAN code, and manufacturer’s suggested retail price (MSRP).
Note: This article is compiled from the official information published by Zeria Pharmaceutical and trusted Japanese pharmaceutical references. It is intended for informational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment.